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Organic compounds that contain a carboxyl group bonded to an organic functional group; carboxyl groups consist of a carbonyl group bonded to a hydroxy group. Includes compounds that are derived from carboxylic acids.
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5-(2-chloroacetamide) thalidomide is a thalidomide analogue that incorporates a thiol-reactive chloroacetamide moiety and is used as an E3 ligase-binding ligand for biochemical and cellular research. The compound is supplied as a solid with reported purity of ≥95.0% and a molecular weight of 349.73 g·mol⁻¹.
Contains a thiol-reactive chloroacetamide group suitable for covalent target engagement.
Useful as an E3 ligase ligand for targeted protein degradation studies.
Supplied as a solid form appropriate for laboratory handling and formulation.